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Overview

How it Works

Features

Publications

FAQ

Real‑time, high‑resolution imaging of dynamic liquid processes directly inside your TEM.

Hummingbird Scientific’s Liquid flow holder allows scientists to image samples in flowing (one or two inlets) or static liquids, up to atomic resolution. It also enables in-situ liquid-electrochemistry and sample heating inside the TEM. This system is a complete, all-in-one liquid environment solution, opening up exciting new avenues for materials characterization.

Technical Specs
Instrument Type
TEM

Available For:

Built on Engineering Excellence

Engineering CapabilitiesCustom Solutions

Built for Diverse Research Applications

Battery Materials

Directly visualize battery cycling, ion transport, dendrite formation, interface evolution, and structural changes.

Charge-Discharge Cycling
Ion Transport
Interface Formation
Dendrite Formation
Failure mechanisms

Bio/Soft Materials

Catalysis

Directly observe the mechanisms that drive catalyst activity, selectivity, and degradation.

Heterogeneous Catalysis
Structure-Performance Relationship
Catalyst Structural Transformations
Catalyst Chemical Transformations
Catalyst Redox

Corrosion/Dissolution

High Impact Publications

Jonas Hallstrom, Puquan Pan, Jayson Sia, Sangwok Bae, Dingwen Qian, Chang Qian, Sindy Liu, Lehan Yao, Thomas M. Truskett, Delia J. Milliron, Qian Chen, Xiaoming Mao, Paul Bogdan, Nicholas A. Kotov. “Decoding collective dynamics and complexity in nanoparticle assemblies using graph theory”. Science (2026)

Abstract

Brenna M. Knight, Biao Jin, Yuna Bae, James J. De Yoreo, Patricia M. Dove. “In situ transmission electron microscopy observations of CaCO3 crystallization onto polysaccharide-coated nanoparticles”. CrystEngComm (2026)

Abstract

Wenhui Wang, Mingyun Zhu, Ivan Erofeev, Guoming Lin, Kuibo Yin, Litao Sun, Utkur Mirsaidov. “Size-Focusing of Au Nanoparticles through Dissolution-Renucleation Process Imaged with In Situ TEM”. Small Methods (2025)

Abstract
Browse All Publications
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Key Features and Capabilities

Cross-Correlative

Our liquid TEM holder's unique removable holder tip allows for multi-modal, correlative imaging.

Vapor System

Continuous Flow

Add-ons

Enhance your in-situ experiments with advanced add-on functionalities

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Related Products

TEM Liquid Flow
Capture nanoscale processes under flowing or static liquid environments with optional biasing, heating, and mixing
SEM Liquid Flow
Capture nanoscale processes under flowing or static liquid environments with optional biasing, heating, and mixing
X-ray Liquid Flow
Capture nanoscale processes under flowing or static liquid environments with optional biasing, heating, and mixing

Awards

Award for Excellence in Technology Transfer

The Federal Laboratory Consortium (FLC) awarded the U.S. Army Engineer Research and Development Center Construction Engineering Research Laboratory for its collaboration with Hummingbird Scientific to develop new in-situ liquid TEM holder technologies including the Liquid Flow Holder.

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Tibbetts Award

Hummingbird Scientific has received a Tibbetts Award from the Small Business Administration (SBA) for the development of a commercially available system—the Liquid Flow Holder—for nanoscale imaging of materials in controlled fluid environments inside the transmission electron microscope.

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