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TEM Liquid Flow

Operando heating, biasing under environmental conditions

Enclosed Flow Cell Inside the TEM

The TEM Liquid Flow sample holder is the first in-situ liquid-phase TEM platform designed to image nanometer-scale liquid-phase reactions and transformations. Our patented precision-machined chip loading mechanism operates without screws, facilitating reproducible sample loading, window alignment, and stable imaging. This simplifies training, workflows, and micrograph acquisition, guaranteeing reproducible sample preparation and in-situ TEM methodologies.
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Advantages:

  • Low-draft sample rod for stable imaging without drift correction
  • Fully user-replaceable liquid tubing for easy cleaning and solution swapping
  • Removable tip for easy cleaning and function upgrades
  • Compatible with TEM, SEM, and X-ray microscopy workflows using cross-platform microfabricated chips.
  • Quick delivery of a broad selection of chip options for uninterrupted experimentation
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Designed for Advanced Nanoscale Liquid-phase Dynamics Research

Investigate mechanisms underpinning the dynamics of particle self-assembly, biomineralization and dissolution, corrosion, nanoparticle-MOF structures, temperature-dependent reactions and thin film electrochemistry in liquid environments.

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Understand Mechanisms Behind Liquid-Phase Transformations

The transformations that occur at liquid-liquid and solid-liquid interfaces are often nanoscale and highly transient, but nanostructure design is highly dependent on the mechanisms that drive these transformations. The TEM Liquid Flow sample holder applies stimuli such as temperature, electrical bias, light exposure, and liquid mixing to uncover reaction pathways, structural transformations, and degradation mechanisms to develop and characterize the next generation of functional nanostructures.

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Technical Specs
1400 series
Number of inlets
1 or 2 depending on model, single outlet
Biasing Contacts
4 on-chip
Tubing Type
User-replaceable microfluidic tubing
Tubing Type Delivery System
Variable speed liquid delivery system
Tip Type
Removable tip
Flow Type
Continuous flow or static liquid
EELS/EDS Compatible
Yes
TEM Compatibility
TFS/FEI, JEOL, Hitachi, Zeiss
Instrument Type
TEM

Available For:

Key Features and Capabilities

Dual-Flow Liquid Mixing

Accelerate discovery with dual-flow liquid mixing for in-situ liquid phase TEM, capturing dynamic liquid-liquid reactions with greater control and flexibility

Integrated Liquid Heating

Add temperature-controlled liquid-phase TEM capabilities with homogeneous heating, precise temperature regulation, and near-drift-free in-situ imaging

60+ In-Stock Liquid-Cell TEM Chip Configurations

Keep experiments moving with in-stock liquid-cell TEM chips designed for electrochemistry, liquid flow, heating, and multimodal microscopy workflows

TEM Safety & Seal Verification

Protect your TEM during liquid-cell experiments and streamline setup with rapid high-vacuum seal checking and optical inspection

Optimized for EELS and EDS

Perform correlative spectroscopy and microscopy for detailed in-situ elemental analysis

Multimodal Imaging

Correlate electrochemical, heating, and imaging data across TEM, SEM, and X-ray microscopy platforms

Removable and swappable tip

Simplify cleaning with removable and upgradeable holder tips that allow access for tubing replacement

Reproducible Screw-Free Liquid-Cell Assembly

Achieve reproducible liquid-cell assembly with self-aligning windows and a screw-free sealing design

Flexible Liquid Cell Operation

Image samples in continuous-flow or static liquid environments using a sealed microfluidic chip assembly

Vapor System

Cross-Correlative

Our liquid TEM holder's unique removable holder tip allows for multi-modal, correlative imaging.

Advanced Configuration Options